题目选项分析

Codex Berinensis, a Florentine copy of an ancient Roman medical treatise, is undated but contains clues to when it was produced. Its first 80 pages are by a single copyist, but the remaining 20 pages are by three different copyists, which indicates some significant disruption. Since a letter in handwriting identified as that of the fourth copyist mentions a plague that killed many people in Florence in 1148, Codex Berinensis was probably produced in that year.

Which of the following, if true, most strongly supports the hypothesis that Codex Berinensis was produced in 1148?

【选项】There was only one outbreak of plague in Florence in the 1100s.