SafeZone mosquito repellant has been shown in laboratory settings to be effective for twelve hours against the female anopheles mosquito, the only mosquito that transmits malaria. SafeZone, however, is not effective against mosquitoes that do not transmit malaria. The only instance in which SafeZone does not repel the female anopheles mosquito is when this mosquito can detect any ruptured blood vessels, a state that inevitably results whenever any kind of mosquito bites a person. Therefore, assuming one does not have any ruptured blood vessels on their skin before applying SafeZone, that person will not be able to catch malaria for up to twelve hours.
Which of the following, if true, would argue most against the use of SafeZone in areas in which malaria is endemic?